Sexual health

PT-141 Tracker

PT-141 is a melanocortin receptor agonist that acts centrally rather than on the vascular system. This page covers its half-life, what that timescale means for keeping a usable record, and how it changes the shape of a log — not what to take or how much.

Recordkeeping reference, not medical guidance. This page describes published pharmacokinetic estimates and how they affect logging. It does not recommend PT-141, any amount, or any schedule, and it is not a claim that this compound is safe, effective, or approved for any use. Talk to a qualified healthcare professional.
Half-life2.7 hrbiological
Activity window12 hrestimated
Time to clear13.5 hr~5 half-lives

What PT-141's timing means for tracking

PT-141 has a half-life near 2.7 hours against an estimated activity window of about 12 — a roughly fourfold gap between how long the compound persists and how long its effects may.

That gap is the useful thing to understand. A record that assumes the effect ends when the compound clears would consistently under-describe the day. It is a milder version of the same divergence seen with TB-500, and the reason PepTrack models both figures rather than plotting decay alone.

Unlike most compounds here, PT-141 is typically used situationally rather than on a fixed recurring schedule. That makes the log look different: irregular by design, with the interval between entries carrying more meaning than any cadence would.

It is also worth noting that bremelanotide is an approved medicine in some markets under the name Vyleesi, which is not true of most compounds on this site.

What to capture in the log

Worked reconstitution example

Purely as arithmetic, using round numbers rather than a recommendation. If a 10 mg vial were mixed with 2 mL of bacteriostatic water, the concentration would be 5 mg/mL. Measuring 1 mg from that would come to:

20 units on a U-100 syringe

10 mg ÷ 2 mL = 5 mg/mL  →  1 mg = 0.2 mL = 20 units

Change either the vial size or the water and this number changes completely. Run your own figures in the reconstitution calculator.

Frequently asked questions

What is the half-life of PT-141?

About 2.7 hours, with an estimated activity window near 12 hours — the effect window is roughly four times the clearance timescale.

Is PT-141 the same as bremelanotide or Vyleesi?

PT-141 and bremelanotide are the same compound; Vyleesi is a brand name under which it is an approved medicine in some markets.

Why is the activity window so much longer than the half-life?

Because they measure different things — how fast the compound clears versus how long the downstream response persists.

How many units is 1 mg of PT-141?

With a 10 mg vial in 2 mL the concentration is 5 mg/mL, so 1 mg is 0.2 mL — 20 units on a U-100 syringe.

Track PT-141 without the mental math

PepTrack stores the schedule, the log, and the concentration together, and draws the estimated level using the same half-life figures shown above. Free on iPhone, no account required.

Download on the App Store